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Article

Development of a tissue augmented Bayesian model for expression quantitative trait loci analysis.

Mathematical biosciences and engineering : MBE - 26 Sept 2019

Zhuang Yong Hua, Wade Kristen, Saba Laura M, Kechris Katerina

Abstract excerpt

Expression quantitative trait loci (eQTL) analyses detect genetic variants (SNPs) associated with RNA expression levels of genes. The conventional eQTL analysis is to perform individual tests for each gene-SNP pair using simple linear regression and to perform the test on each tissue separately ignoring the extensive information known about RNA expression in other tissue(s). Although Bayesian models have been...

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PMID: 31731343
DOI: 10.3934/mbe.2020007
PMCID: PMC7384761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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