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Article

Exploiting expression patterns across multiple tissues to map expression quantitative trait loci.

BMC bioinformatics - 24 Jun 2016

Acharya Chaitanya R, McCarthy Janice M, Owzar Kouros, Allen Andrew S

Abstract excerpt

BACKGROUND: In order to better understand complex diseases, it is important to understand how genetic variation in the regulatory regions affects gene expression. Genetic variants found in these regulatory regions have been shown to activate transcription in a tissue-specific manner. Therefore, it is important to map the aforementioned expression quantitative trait loci (eQTL) using a statistically disciplined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27341818
DOI: 10.1186/s12859-016-1123-5
PMCID: PMC4919894

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