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Article

Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers.

Scientific reports - 14 Nov 2019

Höglund Julia, Rafati Nima, Rask-Andersen Mathias, Enroth Stefan, Karlsson Torgny, Ek Weronica E, Johansson Åsa

Abstract excerpt

Genome-wide association studies (GWAS) have identified associations between thousands of common genetic variants and human traits. However, common variants usually explain a limited fraction of the heritability of a trait. A powerful resource for identifying trait-associated variants is whole genome sequencing (WGS) data in cohorts comprised of families or individuals from a limited geographical area. To evaluate...

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Identifiers

PMID: 31727947
DOI: 10.1038/s41598-019-53111-7
PMCID: PMC6856527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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