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Article

The impact of improved microarray coverage and larger sample sizes on future genome-wide association studies.

Genetic epidemiology - 1 May 2013

Lindquist Karla J, Jorgenson Eric, Hoffmann Thomas J, Witte John S

Abstract excerpt

Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with complex traits. However, the genetic heritability of most of these traits remains unexplained. To help guide future studies, we address the crucial question of whether future GWAS can detect new SNP associations and explain additional heritability given the new availability of larger GWAS SNP arrays,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23529720
DOI: 10.1002/gepi.21724
PMCID: PMC4291231

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