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Article

Human NORs, comprising rDNA arrays and functionally conserved distal elements, are located within dynamic chromosomal regions.

Genes & development - 1 Dec 2019

van Sluis Marjolein, Gailín Michael Ó, McCarter Joseph G W, Mangan Hazel, Grob Alice, McStay Brian

Abstract excerpt

Human nucleolar organizer regions (NORs), containing ribosomal gene (rDNA) arrays, are located on the p-arms of acrocentric chromosomes (HSA13-15, 21, and 22). Absence of these p-arms from genome references has hampered research on nucleolar formation. Previously, we assembled a distal junction (DJ) DNA sequence contig that abuts rDNA arrays on their telomeric side, revealing that it is shared among the...

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Identifiers

PMID: 31727772
DOI: 10.1101/gad.331892.119
PMCID: PMC6942050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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