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Ribosomal DNA arrays are the most H-DNA rich element in the human genome

2024-07-13

Abstract excerpt

Repetitive DNA sequences can form non-canonical structures such as H-DNA which is an intramolecular triplex DNA structure. The new Telomere-to-Telomere (T2T) genome assembly for the human genome has eliminated gaps, enabling the examination of highly repetitive regions including centromeric and pericentromeric repeats and ribosomal DNA arrays. This gapless assembly allows for the examination of the distribution of...

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Literature Corpus work
5461cb6e-e1a0-52d2-a220-5a338124480d
DOI
10.1101/2024.07.12.602585
Open publication

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Ribosomal DNA arrays are the most H-DNA rich element in the human genomeDOI 10.1101/2024.07.12.602585
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