Common Variant in TREM1 Influencing Brain Amyloid Deposition in Mild Cognitive Impairment and Alzheimer's Disease.

doi:10.1007/s12640-019-00105-y

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Common Variant in TREM1 Influencing Brain Amyloid Deposition in Mild Cognitive Impairment and Alzheimer's Disease.

Neurotoxicity research - 1 Mar 2020

Liu Yue-Song, Yan Wen-Jing, Tan Chen-Chen, Li Jie-Qiong, Xu Wei, Cao Xi-Peng, Tan Lan, Yu Jin-Tai

Abstract excerpt

Triggering receptor expressed on myeloid cells-1 (TREM1) has been reported to associate with Alzheimer's disease (AD) pathology. Recently, TREM1 variant rs2234246A was reported to regulate TREM-1 protein and mRNA levels. We explored the effect of rs2234246 on AD specific biomarker (amyloid-β PET) to look into the role of this TREM1 locus in AD pathogenesis. We calculated the association of the TREM1 locus with...

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PMID: 31721052
DOI: 10.1007/s12640-019-00105-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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