Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamics of Spaetzle morphogen shuttling in the Drosophila embryo shapes gastrulation patterning.

Development (Cambridge, England) - 12 Nov 2019

Rahimi Neta, Averbukh Inna, Carmon Shari, Schejter Eyal D, Barkai Naama, Shilo Ben-Zion

Abstract excerpt

Establishment of morphogen gradients in the early Drosophila embryo is challenged by a diffusible sextracellular milieu, and by rapid nuclear divisions that occur at the same time. To understand how a sharp gradient is formed within this dynamic environment, we followed the generation of graded nuclear Dorsal protein, the hallmark of pattern formation along the dorso-ventral axis, in live embryos. The dynamics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Drosophila
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrula

Share to Gastrulation

Share to Intracellular Signaling Peptides and Proteins

Share to Morphogenesis

Share to Phosphoproteins

Source

Identifiers

PMID: 31719046
DOI: 10.1242/dev.181487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamics of Spaetzle morphogen shuttling in the Drosophila embryo shapes gastrulation patterning.PMID 31719046Read ↗

Formation of the BMP activity gradient in the Drosophila embryo.Semantic proximity Read ↗

Biochemical Principles of SMAD Signaling Across the Animal KingdomSemantic proximity Read ↗

The <i>Drosophila</i> pioneer factor Zelda modulates the nuclear microenvironment of a Dorsal target enhancer to potentiate transcriptional outputSemantic proximity Read ↗

The Drosophila ZO-1 protein Polychaetoid suppresses Deltex-regulated Notch activity to modulate germline stem cell niche formation.Semantic proximity Read ↗

Diffusible fraction of niche BMP ligand safeguards stem-cell differentiationSemantic proximity Read ↗

Kinetic analysis of segmentation gene interactions in Drosophila embryos.Semantic proximity Read ↗

Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc.Semantic proximity Read ↗

Diffusible fraction of niche BMP ligand safeguards stem-cell differentiationSemantic proximity Read ↗

Delta, notch, and shaggy: elements of a lateral signaling pathway in Drosophila.Semantic proximity Read ↗

Combinatorial signaling by Twisted Gastrulation and Decapentaplegic.Semantic proximity Read ↗

Nodal is a short-range morphogen with activity that spreads through a relay mechanism in human gastruloidsSemantic proximity Read ↗

Morphogen dynamics control patterning in a stem cell model of the human embryoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.