Article
Combinatorial signaling by Twisted Gastrulation and Decapentaplegic.
Mechanisms of development - 1 Jun 1997
Mason E D, Williams S, Grotendorst G R, Marsh J L
Abstract excerpt
The Twisted Gastrulation (TSG) protein is one of five secreted proteins required to pattern the dorsal part of the early Drosophila embryo. Unlike the Decapentaplegic (DPP) protein that is required to pattern the entire dorsal half of the embryo, TSG is needed only to specify the fate of the dorsal midline cells. Here we have misexpressed the tsg gene with different promoters to address its mechanism of action...
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