Article
The Killer Pseudokinase Mixed Lineage Kinase Domain-Like Protein (MLKL).
Cold Spring Harbor perspectives in biology - 3 Aug 2020
Murphy James M
Abstract excerpt
Whereas the apoptosis cell death pathway typically enables cells to undergo death in an immunologically silent manner, cell death by necroptosis induces cell lysis and release of cellular constituents known to elicit an immune response. Consequently, the origins of necroptosis likely originated in host defense against pathogens, although recently it has emerged that dysregulation of the pathway underlies many...
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