Article
Post-translational control of RIPK3 and MLKL mediated necroptotic cell death
2015-11-19
Abstract excerpt
Several programmed lytic and necrotic-like cell death mechanisms have now been uncovered, including the recently described receptor interacting protein kinase-3 (RIPK3)-mixed lineage kinase domain-like (MLKL)-dependent necroptosis pathway. Genetic experiments have shown that programmed necrosis, including necroptosis, can play a pivotal role in regulating host-resistance against microbial infections. Alternatively...
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Identifiers and source
- Literature Corpus work
- a48e163f-9ea5-5c97-8cb8-a6bf691a13eb
- DOI
- 10.12688/f1000research.7046.1
