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Article

Polygenic risk score for disability and insights into disability-related molecular mechanisms.

GeroScience - 1 Dec 2019

Kulminski Alexander M, Kang Chansuk, Kolpakov Stanislav A, Loika Yury, Nazarian Alireza, Yashin Anatoliy I, Stallard Eric, Culminskaya Irina

Abstract excerpt

Late life disability is a highly devastating condition affecting 20% or more of persons aged 65 years and older in the USA; it is an important determinant of acute medical and long-term care costs which represent a growing burden on national economies. Disability is a multifactorial trait that contributes substantially to decline of health/wellbeing. Accordingly, gaining insights into the genetics of disability...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31707593
DOI: 10.1007/s11357-019-00125-8
PMCID: PMC6925082

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