Article
APOL1 Nephropathy Risk Alleles and Risk of Sepsis in Blacks.
Clinical journal of the American Society of Nephrology : CJASN - 6 Dec 2019
Chaudhary Ninad S, Moore Justin X, Zakai Neil A, Judd Suzanne E, Naik Rakhi P, Limou Sophie, Cushman Mary, Lange Leslie A, Wang Henry E, Winkler Cheryl A, Irvin Marguerite R, Kopp Jeffrey B, Gutiérrez Orlando M
Abstract excerpt
BACKGROUND AND OBJECTIVES: apo L1 (APOL1) nephropathy risk alleles are associated with CKD in blacks. Although APOL1 has innate immune functions, little is known about the association of APOL1 genotypes with risk of infectious outcomes, such as sepsis. The objective of this study was to examine the associations of APOL1 nephropathy risk alleles with risk of sepsis in black adults. DESIGN, SETTING, PARTICIPANTS, &...
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