Article
Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study.
JAMA neurology - 1 Jun 2020
Foo Jia Nee, Chew Elaine Guo Yan, Chung Sun Ju, Peng Rong, Blauwendraat Cornelis, Nalls Mike A, Mok Kin Y, Satake Wataru, Toda Tatsushi, Chao Yinxia, Tan Louis C S, Tandiono Moses, Lian Michelle M, Ng Ebonne Y, Prakash Kumar-M, Au Wing-Lok, Meah Wee-Yang, Mok Shi Qi, Annuar Azlina Ahmad, Chan Anne Y Y, Chen Ling, Chen Yongping, Jeon Beom S, Jiang Lulu, Lim Jia Lun, Lin Juei-Jueng, Liu Chunfeng, Mao Chengjie, Mok Vincent, Pei Zhong, Shang Hui-Fang, Shi Chang-He, Song Kyuyoung, Tan Ai Huey, Wu Yih-Ru, Xu Yu-Ming, Xu Renshi, Yan Yaping, Yang Jing, Zhang BaoRong, Koh Woon-Puay, Lim Shen-Yang, Khor Chiea Chuen, Liu Jianjun, Tan Eng-King
Abstract excerpt
Importance: Large-scale genome-wide association studies in the European population have identified 90 risk variants associated with Parkinson disease (PD); however, there are limited studies in the largest population worldwide (ie, Asian). Objectives: To identify novel genome-wide significant loci for PD in Asian individuals and to compare genetic risk between Asian and European cohorts. Design Setting, and...
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