Article
Genomic Determinants of Clinical Outcomes in Rhabdomyosarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2020
Casey Dana L, Wexler Leonard H, Pitter Kenneth L, Samstein Robert M, Slotkin Emily K, Wolden Suzanne L
Abstract excerpt
PURPOSE: Increased availability of next-generation sequencing has allowed for the genomic characterization of a variety of pediatric tumors, although genomic determinants of response to treatment remain largely unknown. We sought to evaluate the genomic landscape and genomic determinants of clinical outcomes in rhabdomyosarcoma (RMS). EXPERIMENTAL DESIGN: Of 29,067 patients who underwent genomic profiling at our...
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