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Article

Improving Individualized Rhabdomyosarcoma Prognosis Predictions Using Somatic Molecular Biomarkers.

JCO precision oncology - 1 Feb 2025

Zobeck Mark, Khan Javed, Venkatramani Rajkumar, Okcu M Fatih, Scheurer Michael E, Lupo Philip J

Abstract excerpt

PURPOSE: Molecular markers increasingly influence risk-stratified treatment selection for pediatric rhabdomyosarcoma (RMS). This study aims to integrate molecular and clinical data to produce individualized prognosis predictions that can further improve treatment selection. METHODS: Clinical variables and somatic mutation data for 20 genes from 641 patients with RMS in the United Kingdom and the United States...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39913888
DOI: 10.1200/PO-24-00556
PMCID: PMC11801453

Genes

NF1
CDKN2A
EFS
MET
MYCN
MYOD1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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