Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.

doi:10.1200/JCO.20.03060

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Article

Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Sept 2021

Shern Jack F, Selfe Joanna, Izquierdo Elisa, Patidar Rajesh, Chou Hsien-Chao, Song Young K, Yohe Marielle E, Sindiri Sivasish, Wei Jun, Wen Xinyu, Rudzinski Erin R, Barkauskas Donald A, Lo Tammy, Hall David, Linardic Corinne M, Hughes Debbie, Jamal Sabri, Jenney Meriel, Chisholm Julia, Brown Rebecca, Jones Kristine, Hicks Belynda, Angelini Paola, George Sally, Chesler Louis, Hubank Michael, Kelsey Anna, Gatz Susanne A, Skapek Stephen X, Hawkins Douglas S, Shipley Janet M, Khan Javed

Abstract excerpt

PURPOSE: Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent disease remains poor, and beyond PAX-FOXO1 fusion status, no genomic markers are available for risk stratification. We present an international consortium study designed to determine the incidence of driver mutations and their association...

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Identifiers

PMID: 34166060
DOI: 10.1200/JCO.20.03060
PMCID: PMC8425837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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