Article
Artemisinin Bioactivity and Resistance in Malaria Parasites.
Trends in parasitology - 1 Dec 2019
Talman Arthur M, Clain Jérôme, Duval Romain, Ménard Robert, Ariey Frédéric
Abstract excerpt
Artemisinin is the most widely-used compound against malaria and plays a critical role in the treatment of malaria worldwide. Resistance to artemisinin emerged about a decade ago in Southeast Asia and it is paramount to prevent its spread or emergence in Africa. Artemisinin has a complex mode of action and can cause widespread injury to many components of the parasite. In this review, we outline the different...
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