Article
Prognostic impact of tumor mutation burden and the mutation in KIAA1211 in small cell lung cancer.
Respiratory research - 7 Nov 2019
Zhou Mengting, Fan Jun, Li Zhenyu, Li Pindong, Sun Yajie, Yang Yuhui, Zhou Xiaoshu, Wang Jing, Wang Ye, Qi Huiwei, Cai Weijing, Dai Xiaofang, Hirsch Fred R
Abstract excerpt
BACKGROUND: Small cell lung cancer (SCLC) is a highly aggressive lung cancer subtype with poor survival and limited treatment options. Sequencing results have revealed gene mutations associated with SCLC, however, the correlation between the genomic alterations and clinical prognosis of SCLC is yet unclear. METHODS: Targeted next-generation sequencing of 62 cancer related genes was performed on 53 SCLC samples....
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