Article
Tumor Mutational Burden and Genomic Alterations in Chinese Small Cell Lung Cancer Measured by Whole-Exome Sequencing.
BioMed research international - 1 Jan 2019
Su Shan, Zou Jian-Jun, Zeng Yun-Yun, Cen Wen-Chang, Zhou Wei, Liu Yan, Su Duo-Hua, Zhang Xian-Lan, Huang Hui-Yi, Lei An, Huang Zhi-Hao, Jin Yun, Li Lei, Su Ning, Xie Ya-Lin, Zhao Zhen-Gang, Liu Jian-Xiong
Abstract excerpt
PURPOSE: Studies on genetic alterations of the heterogenous small cell lung cancer (SCLC) are rare. We carried out the present study to clarify the genomic alterations and TMB levels of Chinese SCLC patients by whole-exome sequencing. MATERIALS AND METHODS: Whole-exome sequencing by next-generation sequencing technique was implemented on twenty SCLC samples. Significant somatic mutations and copy number...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
