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Significantly mutated genes and regulatory pathways in SCLC-a meta-analysis.

Cancer genetics - 1 Oct 2017

Sundaresan Varsha, Lin Victor T, Liang Faming, Kaye Frederic J, Kawabata-Iwakawa Reika, Shiraishi Kouya, Kohno Takashi, Yokota Jun, Zhou Lei

Abstract excerpt

Small cell lung cancer (SCLC) accounts for approximately 15% of all lung cancers and demands effective targeted therapeutic strategies. In this meta-analysis study, we aim to identify significantly mutated genes and regulatory pathways to help us better understand the progression of SCLC and to identify potential biomarkers. Besides ranking genes based on their mutation frequencies, we sought to identify...

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PMID: 29025592
DOI: 10.1016/j.cancergen.2017.05.003
PMCID: PMC5677515

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