Article
A 3' UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction.
PloS one - 1 Jan 2019
Levran Orna, Randesi Matthew, Rotrosen John, Ott Jurg, Adelson Miriam, Kreek Mary Jeanne
Abstract excerpt
There is a reciprocal relationship between the circadian and the reward systems. Polymorphisms in several circadian rhythm-related (clock) genes were associated with drug addiction. This study aims to search for associations between 895 variants in 39 circadian rhythm-related genes and opioid addiction (OUD). Genotyping was performed with the Smokescreen® array. Ancestry was verified by principal/MDS component...
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