Article
Genome-wide investigation of rare structural variants identifies VIPR2 as a new candidate gene for schizophrenia.
Expert review of neurotherapeutics - 1 Jul 2011
Nieratschker Vanessa, Meyer-Lindenberg Andreas, Witt Stephanie H
Abstract excerpt
Research has shown that structural variation in the human genome, including rare copy number variations (CNVs), contributes to genetic susceptibility to psychiatric diseases, such as schizophrenia, a devastating complex disorder with a high genetic load. The study by Vacic et al. applied a genome-wide approach to detect novel, rare and highly penetrant CNVs. Detailed analysis of microduplications at 7q36.3...
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