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Article

Identification of CD5/Cyclin D1 Double-negative Pleomorphic Mantle Cell Lymphoma: A Clinicopathologic, Genetic, and Gene Expression Study.

The American journal of surgical pathology - 1 Feb 2020

Chuang Wen-Yu, Chang Sheng-Tsung, Yuan Chang-Tsu, Chang Gwo-Jyh, Chang Hung, Yeh Chi-Ju, Ueng Shir-Hwa, Kao Hsiao-Wen, Wang Tong-Hong, Wan Yung-Liang, Shih Lee-Yung, Chuang Shih-Sung, Hsueh Chuen

Abstract excerpt

Pleomorphic mantle cell lymphoma (PMCL) can closely mimic diffuse large B-cell lymphoma (DLBCL) morphologically, and expression of CD5 and cyclin D1 is helpful for differential diagnosis. To date, no cases of CD5/cyclin D1 double-negative PMCL have been reported. Four cases of B-cell lymphoma with an immunophenotype of CD5(-) cyclin D1(-) SOX11(+) and morphologic features compatible with DLBCL were included. Two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Share to In Situ Hybridization, Fluorescence

Share to Lymphoma, Large B-Cell, Diffuse

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Identifiers

PMID: 31688139
DOI: 10.1097/PAS.0000000000001390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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