Article
Large B-cell lymphoma with IRF4 rearrangement: a multi-centric study with focus on potential misleading phenotypes.
Virchows Archiv : an international journal of pathology - 1 Mar 2024
Pizzi Marco, Bongiovanni Lucia, Lorenzi Luisa, Righi Simona, Scarmozzino Federico, Balzarini Piera, Santoro Luisa, Mussolin Lara, Carraro Elisa, Pillon Marta, Bonaldi Laura, Vianello Fabrizio, Agostinelli Claudio, Ponzoni Maurilio, Dei Tos Angelo Paolo, Sabattini Elena
Abstract excerpt
Large B-cell lymphoma with IRF4 rearrangement (LBCL-IRF4) is a rare lymphoid neoplasm, usually occurring in the pediatric/young-adult age. Despite this, subsets of cases occur in elderly patients and express CD5, possibly entering the differential diagnosis with adult aggressive lymphomas, such as blastoid/pleomorphic mantle cell lymphoma (MCL-B/P). To better characterize the clinical-pathological features and...
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