Article
The role of genes affected by human evolution marker GNA13 in schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 2 Mar 2020
Xiang Bo, Yang Juanjuan, Zhang Jin, Yu Minglan, Huang Chaohua, He Wenying, Lei Wei, Chen Jing, Liu Kezhi
Abstract excerpt
Numerous variants associated with increased risk for SCZ have undergone positive selection and were associated with human brain development, but which brain regions and developmental stages were influenced by the positive selection for SCZ risk alleles are unclear. We analyzed SCZ using summary statistics from a genome-wide association study (GWAS) from the Psychiatric Genomics Consortium (PGC). Machine-learning...
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