Association study of the functional Catechol-O-Methyltranferase (COMT) Val158Met polymorphism on executive cognitive function in a Thai sample.

doi:10.7150/ijms.35789

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Article

Association study of the functional Catechol-O-Methyltranferase (COMT) Val158Met polymorphism on executive cognitive function in a Thai sample.

International journal of medical sciences - 1 Jan 2019

Khanthiyong Bupachad, Thanoi Samur, Reynolds Gavin P, Nudmamud-Thanoi Sutisa

Abstract excerpt

Catechol-O-Methyltranferase (COMT) plays a crucial role in the removal of cortical dopamine and is strongly implicated in human executive function. Numerous studies have reported associations of the COMT Val158Met (rs4680) polymorphism with executive function in healthy subjects. However, little work has investigated this in the Thai population and the relationship of age and education with this association...

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PMID: 31673237
DOI: 10.7150/ijms.35789
PMCID: PMC6818203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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