Article
Genetic polymorphisms of IL-10, IL-18 and IL12B are associated with risk of non-small cell lung cancer in a Chinese Han population.
International immunopharmacology - 1 Dec 2019
Zhang Wei, Dang Shengqiang, Zhang Guangjian, He Haiqi, Wen Xiaopeng
Abstract excerpt
PURPOSE: IL-10, IL-18 and IL-12 are reported to participate in the inflammation process. The potential influences of IL-10, IL-18 and IL-12 polymorphisms on non-small cell lung cancer (NSCLC) risk were explored in this study. METHODS: Six candidate SNPs from 500 NSCLC patients and 500 controls were genotyped. The correlation between the SNPs and NSCLC risk was evaluated by logistic regression analysis. RESULTS:...
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