Article
Association of TNFα-308, IFNγ+874, and IL10-1082 gene polymorphisms and the risk of non-small cell lung cancer in the population of the South Indian state of Telangana.
International journal of clinical oncology - 1 Oct 2016
Peddireddy Vidyullatha, Badabagni Siva Prasad, Sulthana Shehnaz, Kolla Venkata Karunakar, Gundimeda Sandhya Devi, Mundluru Hemaprasad
Abstract excerpt
BACKGROUND: Cytokine-mediated inflammation is important in the pathogenesis of non-small cell lung cancer (NSCLC). Genetic polymorphisms in cytokine genes and their association with lung cancer in the Indian population have not been reported. METHODS: For the first time, we analyzed genetic polymorphisms of TNFα -308, IFNγ +874, and IL10 -1082 genes in 246 NSCLC patients and 250 healthy controls in the South...
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