Article
IL1B gene polymorphisms, age and the risk of non-small cell lung cancer in a Chinese population.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2015
Li Yanan, Zhao Wei, Zhao ZhenHong, Wu Junjie, Chen Linqi, Ma Yanyun, Li Qiang, Lu Daru, Jin Li, Wang Jiucun
Abstract excerpt
BACKGROUND/OBJECTIVES: IL1B rs12621220G/A (-3893), rs1143623G/C (-1464), rs16944T/C (-511) and rs1143627C/T (-31) were previously reported to be associated with non-small cell lung cancer (NSCLC) and formed a specific haplotype (GGCT) which was associated with increased IL1B gene expression and increased risk of NSCLC in European populations. Only the two SNPs of rs16944T/C (-511) and rs1143627C/T (-31) have been...
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