Article
Genetic polymorphisms and plasma levels of interleukin-22 contribute to the development of nonsmall cell lung cancer.
DNA and cell biology - 1 Oct 2014
Liu Fei, Pan Xufeng, Zhou Lin, Zhou Jian, Chen Bin, Shi Jianxin, Gao Wen, Lu Liming
Abstract excerpt
Interleukin (IL)-22, a relatively new member of the IL-10 family, has been implicated in inflammation and tumorigenesis. The aim of this study was to identify genetic polymorphisms in IL-22 and to measure plasma levels of IL-22 in patients with nonsmall cell lung cancer (NSCLC). Patients with NSCLC had a significantly higher frequency of IL-22 rs2227484 CT genotype (odds ratio [OR]=1.917, 95% confidence interval...
Topics
- Adenocarcinoma
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Case-Control Studies
- China
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype