Genetic polymorphisms and plasma levels of interleukin-22 contribute to the development of nonsmall cell lung cancer.

doi:10.1089/dna.2014.2432

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Article

Genetic polymorphisms and plasma levels of interleukin-22 contribute to the development of nonsmall cell lung cancer.

DNA and cell biology - 1 Oct 2014

Liu Fei, Pan Xufeng, Zhou Lin, Zhou Jian, Chen Bin, Shi Jianxin, Gao Wen, Lu Liming

Abstract excerpt

Interleukin (IL)-22, a relatively new member of the IL-10 family, has been implicated in inflammation and tumorigenesis. The aim of this study was to identify genetic polymorphisms in IL-22 and to measure plasma levels of IL-22 in patients with nonsmall cell lung cancer (NSCLC). Patients with NSCLC had a significantly higher frequency of IL-22 rs2227484 CT genotype (odds ratio [OR]=1.917, 95% confidence interval...

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PMID: 24956177
DOI: 10.1089/dna.2014.2432

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