Article
Interleukin 17A genetic variations and susceptibility to non-small cell lung cancer.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Mar 2015
Ma Qin-Yun, Chen Ji, Wang Shao-Hua, Wu Ning, Hao Zhen-Hua, Chen Xiao-Feng
Abstract excerpt
Lung cancer is the leading cause of cancer-related death, in which non-small cell lung cancer (NSCLC) is the most common type. Evidence have shown that interleukin 17 (IL-17) greatly involves in human immune responses. In this study, we investigated the effect of IL-17 on NSCLC by examining the association between IL-17A genetic polymorphisms and the susceptibility to NSCLC. IL-17A -420A/G and IL-17A -73G/A...
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