Article

Comparative Analysis of Super-enhancers Across Mammals Reveals Their High Function Conservation

2020-12-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Super-enhancers (SEs) are key positive regulatory elements in defining cells/tissues identity in mammals, yet their similarities and differences of sequence and function across mammals have been poor studied. To allow sequence and function comparison across mammalian SEs, we employ H3K27ac ChIP-seq data to six cell types/tissues across human, pig, and mouse, which...

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Literature Corpus work: 9303b33b-069d-5167-b390-aea9b0703177
DOI: 10.21203/rs.3.rs-121951/v1

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