Article

Summarizing internal dynamics boosts differential analysis and functional interpretation of super enhancers

2021-09-26

Abstract excerpt

<h4>ABSTRACT</h4> Super enhancers (SEs) are broad enhancer domains usually containing multiple constituent enhancers that hold elevated activities in gene regulation. Disruption in one or more constituent enhancers causes aberrant SE activities that lead to gene dysregulation in diseases. To quantify SE aberrations, differential analysis is performed to compare SE activities between cell conditions. The state-of-...

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Literature Corpus work: 91f0960f-9c92-5c7b-ae54-ee65d9f20a54
DOI: 10.1101/2021.09.25.461810

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