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Genome-Wide Transposon Screen of a Pseudomonas syringae mexB Mutant Reveals the Substrates of Efflux Transporters.

mBio - 29 Oct 2019

Helmann Tyler C, Ongsarte Caitlin L, Lam Jennifer, Deutschbauer Adam M, Lindow Steven E

Abstract excerpt

Bacteria express numerous efflux transporters that confer resistance to diverse toxicants present in their environment. Due to a high level of functional redundancy of these transporters, it is difficult to identify those that are of most importance in conferring resistance to specific compounds. The resistance-nodulation-division (RND) protein family is one such example of redundant transporters that are...

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PMID: 31662463
DOI: 10.1128/mBio.02614-19
PMCID: PMC6819667

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