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Article

Mutations in MexB that affect the efflux of antibiotics with cytoplasmic targets.

FEMS microbiology letters - 1 Aug 2012

Ohene-Agyei Thelma, Lea Jon D, Venter Henrietta

Abstract excerpt

Drug efflux pumps such as MexAB-OprM from Pseudomonas aeruginosa confer resistance to a wide range of chemically different compounds. Within the tripartite assembly, the inner membrane protein MexB is mainly responsible for substrate recognition. Recently, considerable advances have been made in elucidating the drug efflux pathway through the large periplasmic domains of resistance-nodulation-division (RND)...

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Identifiers

PMID: 22568688
DOI: 10.1111/j.1574-6968.2012.02594.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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