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Functional interplay between RND efflux pumps and GacS in Pseudomonas aeruginosa

18 Aug 2025

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ABSTRACT Pseudomonas aeruginosa is an opportunistic human pathogen that is ubiquitous in the environment. The environmental versatility of P. aeruginosa is often attributed to a large arsenal of active efflux pumps, low permeability of the outer membrane, and extensive regulatory networks. In this study, we analyzed putative functional interplay between polyspecific drug efflux pumps of the...

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PMID: 40824111
DOI: 10.1128/aem.01223-25

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