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Article

Infection of human T lymphocytes with varicella-zoster virus: an analysis with viral mutants and clinical isolates.

Journal of virology - 1 Feb 2000

Soong W, Schultz J C, Patera A C, Sommer M H, Cohen J I

Abstract excerpt

Varicella-zoster virus (VZV) disseminates in the body in peripheral blood mononuclear cells during chickenpox. Up to 1 in 10,000 mononuclear cells are infected during the viremic phase of the disease. We developed an in vitro system to infect human mononuclear cells with VZV by using umbilical cord blood. In this system, 3 to 4% of T cells were infected with VZV. VZV mutants unable to express certain genes, such...

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Source

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Identifiers

PMID: 10644359
DOI: 10.1128/jvi.74.4.1864-1870.2000
PMCID: PMC111664

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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