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Article

The developmental and pathogenic roles of BAF57, a special subunit of the BAF chromatin‐remodeling complex

5 May 2016

Abstract excerpt

Mammalian SWI/SNF or BAF chromatin-remodeling complexes are polymorphic assemblies of homologous subunit families that remodel nucleosomes. BAF57 is a subunit of the BAF complexes; it is encoded only in higher eukaryotes and is present in all mammalian assemblies. Its main structural feature is a high-mobility group domain, the DNA-binding properties of which suggest that BAF57 may play topological roles as the...

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PMID: 27149204
DOI: 10.1002/1873-3468.12201

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