Article
IRAK2 is associated with systemic lupus erythematosus risk.
Clinical rheumatology - 1 Feb 2020
Boumiza Asma, Zemni Ramzi, Sghiri Rim, Idriss Nadia, Hassine Hana Ben, Chabchoub Elyes, Mzabi Anis, Ghannouchi Neirouz, Bouajina Elyes, Ben Hadj Slama Foued
Abstract excerpt
INTRODUCTION: Interleukin-1 receptor-associated kinases (IRAKs) are serine-threonine kinases involved in toll-like receptor and interleukin-1 signaling pathways. They play a key role in inflammation and innate immunity. IRAKs have been previously incriminated in autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis and inhibition of IRAKs has been recently regarded as a potential...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
