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Article

Multi-locus SNP analyses of interleukin 1 receptor associated kinases 2 gene polymorphisms with the susceptibility to rheumatoid arthritis.

PloS one - 1 Jan 2022

Ghouri Maham, Ismail Muhammad, Zaidi Syeda Areesha, Rehman Shafique, Dahani Asadullah, Saleem Saima, Zehra Sitwat

Abstract excerpt

BACKGROUND: The genetic polymorphisms (rs708035, rs3844283) of Interleukin-1 receptor associated kinases 2 (IRAK2) is involved in the NFκB regulatory pathway. The frequencies of IRAK2 gene are unknown in Pakistani population. Therefore, the study was designed to examine the association of targeted single nucleotide polymorphism(s) in IRAK2 gene of RA patients. METHODOLOGY: The study participants were selected by...

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Identifiers

PMID: 35588430
DOI: 10.1371/journal.pone.0268496
PMCID: PMC9119434

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