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Article

Novel Variants in the IL-38 Gene Shape Genetic Susceptibility in Systemic Lupus Erythematosus.

International journal of rheumatic diseases - 1 Mar 2026

Shu Qingxue, Huang Anfang, He Chengsong

Abstract excerpt

OBJECTIVES: Available evidence has shown a genetic association with systemic lupus erythematosus (SLE) pathogenesis. Interleukin-38 (IL-38) has been found to correlate with SLE development. However, whether IL-38 gene polymorphisms relate to SLE risk needs clarification. METHODS: A total of 390 age- and sex-matched SLE patients and 390 healthy controls were recruited from the Affiliated Hospital of Southwest...

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PMID: 41736261
DOI: 10.1111/1756-185x.70581

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