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Article

MiRNA expression patterns are associated with tumor mutational burden in lung adenocarcinoma

24 Jun 2019

Abstract excerpt

Background: Tumor mutational burden (TMB) has emerged as an independent biomarker to predict patient responses to treatment with immune checkpoint inhibitors (ICIs) for lung adenocarcinoma (LUAD). MicroRNAs (miRNAs) have a crucial role in the regulation of anticancer immune responses, but the association of miRNA expression patterns and TMB is not clear in LUAD.Methods: Differentially expressed miRNAs in samples...

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PMID: 31646073
DOI: 10.1080/2162402x.2019.1629260

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