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Article

miRNA-Based Feature Classifier Is Associated with Tumor Mutational Burden in Head and Neck Squamous Cell Carcinoma.

BioMed research international - 1 Jan 2020

Xia Yu, Wang Qi, Huang Xiaolin, Yin Xinhai, Song Jukun, Ke Zhao, Duan Xiaofeng

Abstract excerpt

Tumor mutation burden (TMB) is considered to be an independent genetic biomarker that can predict the tumor patient's response to immune checkpoint inhibitors (ICIs). Meanwhile, microRNA (miRNA) plays a key role in regulating the anticancer immune response. However, the correlation between miRNA expression patterns and TMB is not elucidated in HNSCC. In the HNSCC cohort of the TCGA dataset, miRNAs that were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33490233
DOI: 10.1155/2020/1686480
PMCID: PMC7787755

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