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Article

Combination of tumor mutation burden and immune infiltrates for the prognosis of lung adenocarcinoma.

International immunopharmacology - 1 Sept 2021

Zhao Zhenyu, He Boxue, Cai Qidong, Zhang Pengfei, Peng Xiong, Zhang Yuqian, Xie Hui, Wang Xiang

Abstract excerpt

BACKGROUND: Tumor mutation burden (TMB) levels are associated with immune infiltrates in the tumor microenvironment and can modulate the responses to immune checkpoint inhibitors (ICIs) in lung adenocarcinoma (LUAD) patients. This study aimed at exploring the potential role of a signature of genes associated with TMB and immune infiltrates and the relevant nomogram in the prognosis of LUAD. MATERIALS AND METHODS:...

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Source

Identifiers

PMID: 34175739
DOI: 10.1016/j.intimp.2021.107807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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