Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An aging-related signature predicts favorable outcome and immunogenicity in lung adenocarcinoma.

Cancer science - 1 Mar 2022

Zhang Wenjing, Li Yuting, Lyu Juncheng, Shi Fuyan, Kong Yujia, Sheng Chao, Wang Suzhen, Wang Qinghua

Abstract excerpt

Aging has been demonstrated to play vital roles in the prognosis and treatment efficacy of cancers, including lung adenocarcinoma (LUAD). This novel study aimed to construct an aging-related risk signature to evaluate the prognosis and immunogenicity of LUAD. Transcriptomic profiles and clinical information were collected from a total of 2518 LUAD patients from 12 independent cohorts. The risk signature was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma of Lung
Share to Aging
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunotherapy

Share to Lung Neoplasms

Share to Lymphocytes, Tumor-Infiltrating

Share to Transcriptome

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 34967077
DOI: 10.1111/cas.15254
PMCID: PMC8898732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An aging-related signature predicts favorable outcome and immunogenicity in lung adenocarcinoma.PMID 34967077Read ↗

Construction and validation of a novel immune and tumor mutation burden-based prognostic model in lung adenocarcinoma.Semantic proximity Read ↗

Exploring the molecular and immune landscape of cellular senescence in lung adenocarcinoma.Semantic proximity Read ↗

Characterization of aging-related profiles in esophageal cancer reveals a signature predicting favorable outcome and immunogenicitySemantic proximity Read ↗

Immune signature-based risk stratification and prediction of immune checkpoint inhibitor's efficacy for lung adenocarcinoma.Semantic proximity Read ↗

Comprehensive analysis of telomere and aging-related signature for predicting prognosis and immunotherapy response in lung adenocarcinomaSemantic proximity Read ↗

Establishment and validation of lung adenocarcinoma aging-related genes prognostic model based on TCGA databaseSemantic proximity Read ↗

Development of a reliable risk prognostic model for lung adenocarcinoma based on the genes related to endotheliocyte senescenceSemantic proximity Read ↗

An Aging-Related Gene Signature-Based Model for Risk Stratification and Prognosis Prediction in Lung Squamous CarcinomaSemantic proximity Read ↗

An Aging-Related Gene Signature-Based Model for Risk Stratification and Prognosis Prediction in Lung AdenocarcinomaSemantic proximity Read ↗

Identification of lung adenocarcinoma subtypes and a prognostic signature based on activity changes of the hallmark and immunologic gene setsSemantic proximity Read ↗

CD8+ T Cell-Associated Gene Signature Correlates With Prognosis Risk and Immunotherapy Response in Patients With Lung AdenocarcinomaSemantic proximity Read ↗

Identification of an immune signature predicting prognosis risk of patients in lung adenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.