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Article

Integrative modeling of multi-omics data for predicting tumor mutation burden in lung cancer patients

2020-07-22

Abstract excerpt

<title>Abstract</title> <p>Background Immunotherapy has been widely used in the treatment of lung cancer, and one of the most effective biomarker for the prognosis of immunotherapy currently is tumor mutation burden (TMB). Although whole-exome sequencing (WES) could be utilized to assess TMB, several problems prevent its routine clinical application. Methods To develop a simplified TMB prediction model, patient...

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Literature Corpus work
096f9298-de42-5a6b-a901-bae5c8f2f3f5
DOI
10.21203/rs.3.rs-45668/v1
Open publication

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