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Article

Rapid fully-automated assay for routine molecular diagnosis of BRAF mutations for personalized therapy of low grade gliomas.

Pediatric hematology and oncology - 1 Feb 2020

Merlin Marie-Sophie, Gilson Pauline, Rouyer Marie, Chastagner Pascal, Doz François, Varlet Pascale, Leroux Agnès, Gauchotte Guillaume, Merlin Jean-Louis

Abstract excerpt

Background: BRAF mutation analysis is important to personalize the management with low-grade gliomas (LGG) in children and adults, with therapeutic and prognostic impacts. In recurrent tumors, targeted therapies such as BRAF inhibitors had been reported to induce disease stabilization and significant radiographic responses. This highlights the potential interest of BRAF mutation to stratify patients for targeted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31642744
DOI: 10.1080/08880018.2019.1679304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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