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Article

Multicenter Evaluation of a Novel Automated Rapid Detection System of BRAF Status in Formalin-Fixed, Paraffin-Embedded Tissues.

The Journal of molecular diagnostics : JMD - 1 May 2016

Schiefer Ana-Iris, Parlow Laura, Gabler Lisa, Mesteri Ildiko, Koperek Oskar, von Deimling Andreas, Streubel Berthold, Preusser Matthias, Lehmann Annika, Kellner Udo, Pauwels Patrick, Lambin Suzan, Dietel Manfred, Hummel Michael, Klauschen Frederick, Birner Peter, Möbs Markus

Abstract excerpt

The mutated BRAF oncogene represents a therapeutic target in malignant melanoma. Because BRAF mutations are also involved in the pathogenesis of other human malignancies, the use of specific BRAF inhibitors might also be extended to other diseases in the future. A prerequisite for the clinical application of BRAF inhibitors is the reliable detection of activating BRAF mutations in routine histopathological...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26921540
DOI: 10.1016/j.jmoldx.2015.12.005

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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