Article
BRAF mutation testing with a rapid, fully integrated molecular diagnostics system.
Oncotarget - 29 Sept 2015
Janku Filip, Claes Bart, Huang Helen J, Falchook Gerald S, Devogelaere Benoit, Kockx Mark, Bempt Isabelle Vanden, Reijans Martin, Naing Aung, Fu Siqing, Piha-Paul Sarina A, Hong David S, Holley Veronica R, Tsimberidou Apostolia M, Stepanek Vanda M, Patel Sapna P, Kopetz E Scott, Subbiah Vivek, Wheler Jennifer J, Zinner Ralph G, Karp Daniel D, Luthra Rajyalakshmi, Roy-Chowdhuri Sinchita, Sablon Erwin, Meric-Bernstam Funda, Maertens Geert, Kurzrock Razelle
Abstract excerpt
Fast and accurate diagnostic systems are needed for further implementation of precision therapy of BRAF-mutant and other cancers. The novel IdyllaTMBRAF Mutation Test has high sensitivity and shorter turnaround times compared to other methods. We used Idylla to detect BRAF V600 mutations in archived formalin-fixed paraffin-embedded (FFPE) tumor samples and compared these results with those obtained using the...
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